Symbol
Name
ID

Tnfrsf1b
tumor necrosis factor receptor superfamily, member 1b
MGI:1314883

Phenotype annotations related to immune system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Hepatosplenomegaly	Helicobacter pylori infection	Nephritis	Autoimmunity
Disease(s) Associated with TNFRSF1B	Hepatosplenomegaly	Helicobacter pylori infection	Nephritis	Autoimmunity
IgA glomerulonephritis
pre-eclampsia

Mouse Phenotypes

immune system phenotype

decreased T cell proliferation

periinsulitis

decreased T cell number

microgliosis

increased circulating tumor necrosis factor level

abnormal immune system physiology

decreased interferon-gamma secretion

decreased interleukin-2 secretion

decreased susceptibility to autoimmune diabetes

increased susceptibility to experimental autoimmune encephalomyelitis

increased inflammatory response

lung inflammation

decreased susceptibility to bacterial infection

increased susceptibility to bacterial infection

increased susceptibility to parasitic infection

Availability

Mouse Genotype

Tnfrsf1b^{tm1a(EUCOMM)Wtsi}/Tnfrsf1b^{tm1a(EUCOMM)Wtsi}

Tnfrsf1b^tm1Imx/Tnfrsf1b^tm1Imx

Tnfrsf1b^tm1Mwm/Tnfrsf1b^tm1Mwm

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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